Toxicology
Based on OECD guidelines/ customized protocols
Acute oral/dermal and Inhalation toxicity study
Eye irritation study
MTD studies in rodents and non-rodents
Skin and eye irritation study
Skin sensitization study
Chronic
28/90/180 Days Repeated Dose Toxicity
Carcinogenicity /chronic Toxicity Studies/ Combined Chronic/ Neurotoxicity Studies
Juvenile Toxicity
DRF in rodents and non-rodents
Genetic Toxicity Studies
Reverse Mutation Assay (Ames Assay)
Ames test – Using 2 or 5 strains of Salmonella Typhimurium
Micronucleus Test (MNT)
In-Vivo Mammalian Erythrocyte Micronucleus Test in Mice
Chromosomal Aberration Assay
In-Vitro Mammalian Chromosome Aberration Test
Skin irritation test & Cytotoxicity study
Sensitization Assay
Alternative to animal study
In Vitro Ocular Irritation Test (EpiOcularTM)
In Vitro 3T3 NRU Phototoxicity
Dermal absorption study, Photo toxicity and Irritation study
Isolated tissue studies & Chicken Eye Test
In Vitro Ocular Irritation Test (EpiOcularTM)
In Vitro Skin Irritation Test (EpiskinTM/EpidermTM)
In Vitro Dermal absorption (EpiskinTM/EpidermTM) / Human Cadaver Skin/Porcine skin/Cornea
Local Lymph Node Assay (LLNA): BrdU-ELISA
Direct Peptide Reactivity Assay (DPRA)
Pathology Services
We provide independent pathology services, which includes –
Necropsy and Gross Pathology
Histopathology slide preparation and evaluation
Hematoxylin and Eosin (H & E) Staining and Special Staining’s (as per requirement)
Immunohistochemistry, Hematology, Clinical Chemistry
Clinical Pathology & Urinalysis
