Our metabolic research services at Skanda Life Sciences encompass a wide range of in Our metabolic research services at Skanda Life Sciences encompass a comprehensive array of in vitro assays and pre-clinical models to advance drug discovery in metabolic disorders.
Metabolic disorders
Our metabolic research services at Skanda Life Sciences encompass a wide range of in Our metabolic research services at Skanda Life Sciences encompass a comprehensive array of in vitro assays and pre-clinical models to advance drug discovery in metabolic disorders. From hepatocyte cultures for studying liver metabolism to adipocyte assays for investigating obesity-related pathways, our approach enables precise evaluation of drug candidates. With a commitment to scientific excellence and innovation, we aim to address the global burden of metabolic diseases by understanding their underlying mechanisms and developing novel therapeutics.
In Vitro Assays:
Glucose Uptake Assays
Measure the rate of glucose uptake by cells, providing insights into cellular glucose metabolism.
Insulin Sensitivity/ Release Assays
Evaluate the sensitivity of cells to insulin, a key regulator of glucose metabolism, to understand insulin signalling pathways and insulin resistance.
Mitochondrial Function Assays: Examine mitochondrial activity and function to study cellular energy production and mitochondrial dysfunction in metabolic diseases. Skanda has a collection of gold standard in vitro models to support the above research
Lipid Accumulation Assays
Assess lipid accumulation in cells to study lipid metabolism and its dysregulation in metabolic disorders.
3T3-L1 Adipocytes
3T3-L1 Adipocytes are employed in explore adipocyte differentiation, lipid metabolism, and adipokine secretion in obesity and metabolic syndrome research.
C2C12 Myotubes
C2C12 Myotubes are used in investigative research of skeletal muscle metabolism, glucose uptake, and insulin signalling pathways in diabetes and insulin resistance research.
HepG2 Hepatocytes
Examine hepatic lipid metabolism, gluconeogenesis, and drug metabolism in liver-related metabolic disorders.
MIN-6 Cells
MIN-6 Cells helps study pancreatic beta cell function, insulin secretion, and glucose metabolism in diabetes and insulin resistance research.
RIN Cells
RIN Cells are used to investigate pancreatic islet cell physiology, insulin production, and glucose-stimulated insulin secretion in diabetes research.
L6 Cells
L6 Cells are used to explore skeletal muscle glucose uptake, glycogen metabolism, and insulin signalling in diabetes and exercise physiology research.
In vitro metabolic research is crucial for early-phase drug discovery, enabling the identification of drug targets, screening of therapeutics, and assessing efficacy and safety. Skanda integrates advanced technology platforms and expertise to advance understanding and develop therapies for metabolic diseases.
High-Throughput Screening (HTS) Platforms
Rapid screening of large compound libraries to identify potential drug candidates targeting metabolic pathways.
Advanced Techniques
Utilization of advanced techniques such as FRET, TR-FRET, qPCR, Western blot, and spectrophotometry to further enhance the understanding of cellular metabolism and drug effects.
Our Metabolic Research Service Model empowers researchers to accelerate the discovery and development of new treatments for metabolic disorders, driving innovation and progress in the field of metabolic research.
