Agrochemicals
Cosmetics
Skin Lightening & Sunscreen
- Evaluation of melanin inhibitory properties against UV induced melanin synthesis.
- In-vitro antioxidant activity (LPO).
- Determination of SPF factor
- Evaluation of modulatory effect on MITF, TRP-1 and DCT gene expression in melanocytes
- Mushroom Tyrosinase Inhibitory assay
Moisturizing & Soothing
- In-vitro antioxidant studies
- In-vitro cytoprotective activity against UV induced DNA damage in keratinocytes.
- In -vitro anti-inflammatory studies.
- Evaluation of modulatory effect on AQP-3, p53, collagen and elastin gene expression in keratinocytes.
Anti-Aging & Anti-Wrinkle
- In-vitro antioxidant studies.
- Cytoprotective effect against UV induced cell damage.
- Evaluation of protective role against photo aging.
- Modulatory effect on collagen biosynthesis in dermal fibroblasts.
- Evaluation of modulatory effect on Collagen, Elastin and MMP-9 gene expression in dermal fibroblasts.
Psoriasis
- Effect of product on proliferation on HaCaT cell line
- Effect of Nitric oxide generation in THP-1 cells
- Determination of apoptotic activity of test substance in HaCaT cell line by DNA fragmentation analysis
- In-vivo anti-psoriatic activity in rat tail model
Anti-Acne
- In-vitro inhibitory studies against P. acne.
- In-vitro anti-inflammatory studies.
- Evaluation of modulatory effect on 5α reductase, IL-8 and MMP-1 gene expression
Wound Healing
- Effect on cell migration by scratch model in fibroblasts.
- In-vitro anti-inflammatory studies.
- Evaluation of modulatory effect on IL-6, IL-8 and MMP-2 gene expression
Oral Care
- Studies against oral bacteria (Staphylococcus sp) & streptococcus sp
- Studies against Gingivitis causing bacteria
- Modulatory effect on Lactobacillus sp
Disinfectants & Preservatives
- Anti-microbial studies.
- Time Kill assay.
- Contact kill assay.
- Preservative Efficacy Test (PET)
Hair Care
- Anti-dandruff studies against furfur and C. albicans
- Cell proliferation assay.
- Evaluation of modulatory effect on 5α reductase, collagen, laminin, IL-8, SHH gene and ECM protein expression in keratinocytes.
In-vivo Anti-hair fall study
- In-vivo Anti-hair fall study on test product using androgenic alopecia rat model.
Parameters analyzed:
- Physical parameters
- Hair length
- Hair density (no. /mm)
- Biochemical parameters
- Total protein in blood serum
- Total leucocytes count (WBC)
- Histopathology of skin
Clinical Trials
- Skanda offers clinical trial studies as per Clinical Trials Registry – India (CTRI) and has a healthy volunteer base of 1000 individuals.
- Skanda has successfully completed more than 40 clinical trials for skin care and cosmetics.
- We have experienced Cosmetic Surgeons in our advisory research team who can help in the design of experimentation and associated with many reputed hospitals for volunteers.
