Global Calcium is one of the leading manufacturers and exporters of Magnesium Sulphate CAS no. 10034-99-8, API, (Active Pharmaceutical Ingredient). We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.

As manufacturer of Magnesium Sulphate we hereby state the following facts about the drug:

Indications for Use

Treatment of severe toxemias (pre-eclampsia) of pregnancy and acute nephritis in children.

Magnesium sulfate injection is indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia.

In animals indicated for tetany treatment and uterine tetany as a myometrial relaxant.

Mechanism of Action

Magnesium sulfate reduces striated muscle contractions and blocks peripheral neuromuscular transmission by reducing acetylcholine release at the myoneural junction. Additionally, Magnesium inhibits Ca²⁺ influx through dihydropyridine-sensitive, voltage-dependent channels. This accounts for much of its relaxant action on vascular smooth muscle.

Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market